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KMID : 0368820180570030230
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Journal of the Korean Neuropsychiatr Association
2018 Volume.57 No. 3 p.230 ~ p.234
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Treatment-Resistant Schizophrenia : Pathophysiology and Treatment
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Kim Eui-Tae
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Abstract
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A large proportion of patients with schizophrenia show a poor response to first-line antipsychotic drugs, which is termed treatment-resistant schizophrenia. Previous studies found that a different neurobiology might underlie treatment-resistant schizophrenia, which necessitates the development of different therapeutic approaches for treating treatment-resistant schizophrenia. This study reviewed previous studies on the pathophysiology of treatment-resistant schizophrenia and the pharmacological intervention, and forthcoming investigations of treatment-resistant schizophrenia are suggested
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KEYWORD
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Treatment-resistant, Schizophrenia, Neurobiology, Strategy
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